The possibility of using different variants HPLC in determining baclofen in biological objects
Olga Dukova, Efim Krasnov, Mihail Kotlovsky, Elena Suvorova, Aleksandr Efremov
Abstract
The possibilities of determination baclofen in biological fluids (blood, urine) HPLC detection of different variants for diagnostics of poisoning baclofen are considered. For identification and quantitative determination baclofen in urine proposed a method based on HPLC-UV. For the quantitative determination baclofen in blood developed the technique HPLC-MS/MS. The developed techniques are sensitive, express, specific and accurate.