The Determination of the content of the R-isomer of salbutamol sulphate in a solution by the UV-spectroscopy method
Alexandra Viktorovna Sysoeva, Natalya Grigor`evna Bazarnova, Dmitriy Alekseevich Karpitskiy, Petr Sergeevich Kuznetsov, Evgeny Yurievich Kushnir, Nikolay Ivanovich Petrin, Alexander Vladimirovich Sysoev, Marina Yuiryevna Tcheprasova, Irina Vladimirovna Mikushina
Abstract
A spectroscopic method for quantifying the content of the R-isomer of salbutamol sulfate in a methanol solution obtained by separation of the racemic salt by preparative supercritical fluid chromatography has been developed. The proposed method is characterized by express, high sensitivity, the ability to analyze very dilute solutions and simplicity of equipment.