Physicochemical and catalytic properties of 4.0% Mo/ZSM-5 catalysts manufactured on the basis of zeolites with a hierarchical pore system are investigated. The effect of the conditions of synthesis of zeolites with an additional mesoporous structure on their textural and acidic characteristics is studied. The structure and morphology of crystals of synthesized zeolites and catalysts produced from them are determined by the methods of X-ray diffraction analysis and high-resolution scanning transmission electron microscopy. It is shown that 4.0% Mo/ZSM-5 catalysts produced from zeolites with a mesoporous structure exhibit higher activity and stability in the course of methane dehydroaromatization.