NEW SULFAMIDES BASED ON 1-IZOPROPIL-3-α-NAFTYL-5-METHOXYMETHYL-4-AMINOPYRAZOLE AND DETERMINATION OF IT’S STRUCTURE
Ilya G Povarov, Nikita A Shilenkov, Ekaterina V Neupokoeva, Ivan V Peterson, Georgy A Suboch, Alexey V Lubyashkin, Mikhail S Tovbis
Abstract
For the previously obtained 1-isopropyl-3-α-naphthyl-5-methoxymethyl-4-nitrosopyrazole, a reduction reaction with hydrazine hydrate was performed. It was first synthesized by 1-isopropyl-3-α-naphthyl-5-methoxymethyl-4-aminopyrazole, which was then sulfonylated by p-acetamidobenzenesulfonyl chloride and p-toluenesulfonic chloride. As a result, previously unknown sulfonylated derivatives of N-alkylated aminopyrazoles were obtained. The composition and structure are confirmed by modern methods of analysis, such as IR, 1H NMR spectroscopy and mass spectrometry.