A study of the bactericidal action of a number of phytopreparations obtained as a result of mechanochemical treatment of mixtures of plant raw materials with solid sodium carbonate in relation to 10 species of opportunistic bacteria was carried out. The investigated phytopreparations have a selective effect on 1-3 types of microorganisms. The effect of the additive action of phytopreparations in mixtures, which can be used for the prevention and treatment of diseases of animals and humans with an established bacterial etiology, has been discovered.