The data about diversity and occurrence of skeletal abnormalities of Siberian grayling’s larvae and juveniles from the Mana river (Middle Yenisei River system), obtained under the temporary fish-breeding farm, as well as in fishes developing in vivo. The aim of the present work was to study the qualitative and quantitative characteristics of the basic forms of skeletal malformations in juvenile Siberian grayling from the Mana river developing under natural and artificial reproduction.The first describes the qualitative and quantitative characteristics of morphological abnormalities in the Siberian grayling in aquaculture.