SYNTHESIS OF SULFONYLATED 4-AMINO-1H-PYRAZOLES WITH ARYL AND METHOXYMETHYL SUBSTITUENTS
Ilya G Povarov, Alexey V Lyubyashkin, Anna S Kositsyna, Georgy A Suboch, Mikhail S Tovbis
Abstract
The experimental data on the sulfonylation of 4-amino-1H pyrazoles with p-toluenesulfonyl chloride are given in the paper. New compounds were obtained: 3,5-dimethyl-4-tosylamino-1H-pyrazole, 3-methoxymethyl-5-phenyl-4-tosylamino-1H-pyrazole, 3-methoxymethyl-5-naphthyl-4-tosylamino-1H-pyrazole, 3-methyl- 5-naphthyl-4-tosylamino-1H-pyrazole . The structure of sulfonylated aminopyrazoles was proved by IR, UV, 1H NMR spectroscopy and mass spectrometry.