Methods and ways of pathology diagnostics in different organs and systems of human being dealing with connective tissue dysplasia (СTD) are discussed. Number of some compounds such as biomarkers are proposed for evaluation of morphological and functional breaking of visceral and locomotive  motor organs associated with (СTD).  Perspective activity of the Centre for Collective Work’s (Siberian Federal University) facilities for working out  new methods of biomarkers’ determination has been  underlined.