This paper examines the marijuana usage among university students in Ghana. A focused interview was done to solicit information from users of the drug. It paid attention to thematic areas that are replete in the existing literature concerning the use of marijuana and its ramifications on student users of the drug. Attention is paid to the factors that drive the students to use the drug and its ramifications on their performance as students. Results and discussions that emanated from this severally qualitative study with some quantitatives should serve as bases for university administrators and lecturers to see the need to enhance their efforts in training peer educators and counseling units in universities in Africa and Ghana in particular.